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Botulinums / Diluents

BOTOX® is used for both aesthetic and therapeutic treatments that temporarily makes moderate to severe frown lines, crow’s feet, and forehead lines look better in adults. Botox Cosmetic OnabotulinumtoxinA injections are noted primarily for the ability to reduce the appearance of facial wrinkles. They’re also used to treat conditions such as neck spasms (cervical dystonia), excessive sweating (hyperhidrosis), an overactive bladder and lazy eye. Botox injections may also help prevent chronic migraines.

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What is Botox

Botox Cosmetic is an injectable wrinkle muscle relaxer. It uses botulinum toxin type A, specifically OnabotulinumtoxinA, to temporarily paralyze muscle. This reduces the appearance of facial wrinkles.

A Botox treatment is considered a safe, effective treatment for fine lines and wrinkles around the eyes. It can also be used on the forehead between the eyes.

Botox was originally FDA approved in 1989 for the treatment of blepharospasm and other eye muscle problems. In 2002, the FDA approved the use of Botox for a cosmetic treatment for moderate to severe frown lines between the eyebrows. It was approved by the FDA for treatment of wrinkles around the corners of the eyes (crow’s feet) in 2013.

Preparing for Botox Cosmetic

Botox Cosmetic involves a nonsurgical, in-office treatment. It requires minimal preparation. You should let your treatment provider know about your medical history, allergies, or medical conditions before your procedure. Your treatment provider should be a licensed physician, a physician assistant, or a nurse.

Clinicians use Botulinum toxin by diluting the powder in saline and injecting it directly into neuromuscular tissue.

It takes 24–72 hoursTrusted Source for the toxin to take effect. Rarely, it can take as long as 5 days for the full effects to show. They may last 3–12 months, depending on the treatment.

People should avoid using Botox during pregnancy or breastfeeding, or if they have ever had an allergic reaction to the drug or any of its ingredients.

How does Botox work?

Botox is a neurotoxin. These substances target the nervous system, disrupting the nerve signaling processes that stimulate muscle contraction. This is how the drug causes temporary muscle paralysis.

In order for any muscle to contract, the nerves release a chemical messenger called acetylcholine at the junction where nerve endings meet muscle cells. Acetylcholine attaches to receptors on the muscle cells and causes the cells to contract, or shorten.

Botox injections prevent the release of acetylcholine, which stops the muscle cells from contracting. In this way, the toxin helps the muscles to become less stiff.

Botox Injection for Solution

BOTOX® is also injected into the skin to treat the symptoms of severe underarm sweating (severe primary axillary hyperhidrosis) when medicines used on the skin (topical) do not work well enough in people 18 years and older.

BOTOX® Cosmetic is a prescription medicine that is injected into muscles and used to temporarily improve the look of moderate to severe forehead lines, crow’s feet lines, and frown lines between the eyebrows in adults.

It is not known whether BOTOX® and BOTOX® Cosmetic are safe and effective to prevent headaches in patients with migraine who have 14 or fewer headache days each month (episodic migraine).

BOTOX® has not been shown to help people perform task-specific functions with their upper limbs or increase movement in joints that are permanently fixed in position by stiff muscles.

It is not known whether BOTOX® and BOTOX® Cosmetic are safe and effective for severe sweating anywhere other than your armpits.

It is not known if BOTOX® Cosmetic is safe and effective for use more than 1 time every 3 months.

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